Thursday, January 24, 2013

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Source: http://thegayte-keeper.blogspot.com/2013/01/colorado-springs-investment-property.html

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Apple's profit rocket hits air pocket

FILE - In this Oct. 20, 2012 photo, people line up to enter a newly-opened Apple Store in Wangfujing shopping district in Beijing. Apple's profit surge halted in the latest quarter, as a flood of new products like the iPhone 5 meant high start-up costs for new production lines. Apple posted net income for the October to December quarter that was flat with the year before. It was the first time in years that Apple didn't post a double-digit earnings increase. (AP Photo/Andy Wong, File)

FILE - In this Oct. 20, 2012 photo, people line up to enter a newly-opened Apple Store in Wangfujing shopping district in Beijing. Apple's profit surge halted in the latest quarter, as a flood of new products like the iPhone 5 meant high start-up costs for new production lines. Apple posted net income for the October to December quarter that was flat with the year before. It was the first time in years that Apple didn't post a double-digit earnings increase. (AP Photo/Andy Wong, File)

NEW YORK (AP) ? Apple's blockbuster revenue growth is slowing drastically, as iPhone sales plateau and the company finds itself lacking revolutionary new products.

The company's warning, issued Wednesday as part of its financial results for the holiday quarter, sent Apple Inc.'s stock plunging by more than 10 percent, wiping out a year's worth of gains.

Analysts said the warning suggested Apple can no longer sustain its growth without some completely new products. Its last revolutionary creation, the iPad, was launched in 2010. Co-founder Steve Jobs, who was the engine behind the creation of the iPod, iPhone and iPad, died in 2011.

"It has been an overriding concern with Apple that they would not be able to generate revenue growth just rolling out new versions of old products," said Jeff Sica, president and chief investment officer of SICA Wealth Management. "Now they've proven it in their numbers."

On a conference call with analysts, Apple CEO Tim Cook rebutted that idea, but as usual, gave no details.

"We're working on some incredible stuff. The pipeline is chock full," he said.

Before he died in 2011, Apple co-founder Steve Jobs told biographer Walter Isaacson that he had figured out how to create a groundbreaking, easy-to-use TV set. Since then, company watchers have been waiting for the company to bring out something in that vein to re-energize sales. Cook said the company was still working on it.

"I tend to believe that there's a lot we can contribute in the space, and so we continue to pull the string and see where it leads us," he said.

Apple said it expects sales of between $41 billion and $43 billion in the current quarter, which ends in March. That would usually be little cause for concern, even though analysts were expecting $45.6 billion, because Apple usually lowballs its forecasts. But Chief Financial Officer Peter Oppenheimer said the company is changing its practices and providing a reasonable range rather than a single, easily achievable number.

That means Apple is looking at sales growth of about 7 percent from last year's January to March quarter, a striking number for a company that's posted double-digit increases in every quarter except one since 2008.

Apple's stock fell $55.58 to $458.43 in extended trading, after the release of the results. The shares are down 35 percent from their all-time high, hit Sept. 21, when the iPhone 5 launched.

Fueled by earlier versions of the iPhone, Apple's market capitalization decisively overtook that of Exxon Mobil in early 2012, making it the world's most valuable company. With Wednesday's drop, Apple is worth just 5 percent more than Exxon.

Apple's enviable profit growth also hit a wall in the October to December quarter. It said net income in the fiscal first quarter was $13.1 billion, or $13.81 per share, flat with a year ago. That still beat expectations, as analysts polled by FactSet had forecast earnings of $13.48 per share.

Revenue was $54.5 billion, up 18 percent from a year ago. Analysts were expecting $55 billion. Sales were held back by the fact that the latest quarter had 13 weeks, one less than the corresponding 2011 quarter.

Apple shipped 47.8 million iPhones in the quarter, about 1 million less than analysts were expecting, and 22.9 million iPads, also about 1 million short.

Most surprisingly, Mac sales were also 1 million short, at 4.1 million. That's a 22 percent drop from shipments a year ago. Oppenheimer said this was because Apple couldn't get the new iMac desktops out before December.

Cook said iPhone supplies were short too, and the company could have sold more of both the iPhone 5 and older iPhone 4 if it had been able to make more.

Most technology companies would be ecstatic if they posted 18 percent sales growth and $13 billion in profit for a single quarter, but Apple is held to a high standard, set by the shocking, iPhone-propelled success of the last few years.

"Apple has been growing tremendously and that level of growth can't be sustained by any company," said Sarah Rotman Epps, senior analyst at Forrester Research.

Investors have already been concerned that Apple's strategy of keeping the price of the iPhone high means it's losing out on sales, particularly overseas. Consumers are instead opting to buy cheaper smartphones running Google Inc.'s Android software, which has propelled South Korea's Samsung Electronics to the world's largest maker of smartphones. The average wholesale price of the iPhone is $640, hundreds of dollars more than smartphones with comparable hardware.

There's speculation among company watchers that the company will produce a cheaper iPhone, but that would cut into its profit margin and could tarnish the company's image as a purveyor of premium products.

Apple had warned that the holiday quarter's profits would be lower than Wall Street was initially expecting, because it had so many new products coming out, including the iPhone 5 and iPad Mini. New production lines are more expensive to run and yield more defective products that need to be redone or thrown out rather than sold.

___

AP Technology Writer Barbara Ortutay contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-01-23-Earns-Apple/id-c659582e910e4b5799a6698414cdcc10

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Wednesday, January 23, 2013

Netflix Shares Jump 30% After Hours, As It Beats The Street With Revenues Of $945M And 2M New Subscribers

netflixbuilding4Netflix had a stellar fourth quarter, posting revenues and subscriber numbers well above analyst estimates. That has got investors excited again, driving the stock up 25 percent in after hours trading. Netflix had a better-than-expected fourth quarter, posting revenues and subscribers above analyst estimates. In its earnings report, the company announced $945 million for the quarter.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/8tfXR2Fu7GE/

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Tuesday, January 22, 2013

New Mexico teen accused of killing family wanted to kill more, police ...

By Matthew DeLuca, Staff Writer, NBC News

A 15-year-old New Mexico boy accused of fatally shooting his parents and three of his siblings told his girlfriend they had died in a car crash, according to a probable cause document released Monday to KOB News 4.

Police said the boy, Nehemiah Griego, later admitted during questioning that he shot his mother, brother and two sisters ? who were 9 and younger ? then waited to shoot his father, a popular Albuquerque chaplain who was not home at the time, according to the court document.

Nehemiah agreed to speak with police without an adult or lawyer present, according to the court document. Police have not confirmed whether the teen, who was booked in juvenile jail, has been assigned a public defender.


Nehemiah was charged Sunday morning with five counts of murder and three counts of child abuse leading to death. Under New Mexico state law, 15-year-olds charged with first-degree murder are tried in adult criminal court.?

What Nehemiah allegedly told police is laid out in the probable cause statement for his arrest that was filed in Bernalillo County Children?s Court Division on Sunday.?

Police were called to the Griego residence in a rural Albuquerque neighborhood on Saturday after receiving a call from a parishioner at Cavalry Church, a local Christian parish where Nehemiah?s father, Greg Griego, had once served as a pastor.

Nehemiah had been at the church and had told his girlfriend that his family had been killed in a car accident. He said that girlfriend's grandmother started asking questions and that he was later called to his pastor's office.?

Church officials, suspicious of the story, called police. Nehemiah initially told police that he had returned home from a friend?s house at 5:30 a.m. on Saturday to find the door to his house locked, according to the document. He told police that he found his father?s "carcass" on the ground floor.?

After finding his mother and brother?s body on his parent?s bed, he then took a set of car keys from his mother?s purse and drove the family van to the church, the document said.?

Arriving at the home, police found five bodies ? later identified as those of Greg Griego, 51, Sarah Griego, 40, and three of their 10 children Zephania, 9, Jael, 5, and Angelina, 2. The other children were not home, according to the Albuquerque Journal.

'Horrific' scene after teen allegedly shoots parents, siblings

Griego then changed his story, according to the document, after police asked him why he had driven to the church with two rifles in the van, and why he had not called 911. He said that he did not call 911 because he panicked.

Nehemiah told them that he had been having suicidal and homicidal thoughts. He said he shot his mother with a .22 rifle around midnight as she slept. He said his 9-year-old brother woke up after the gunfire and that he told him he had just shot their mother.

"Nehemiah stated his brother did not believe him so Nehemiah picked up his mother's head to show his brother her bloody face," the statement said. "Nehemiah stated his brother became upset so he shot his brother in the head with the same rifle he used to shoot his mother."?

He then went into the bedroom his two younger sisters share and found them crying. He told police that he shot both of them in the head. Then he said that he went downstairs and waited for his father to return. His father returned at 5 a.m. that morning.

Nehemiah told police he shot his father multiple times with an AR-15 semi-automatic rifle with a scope, according to the document, then said he reloaded the weapons with the intention of driving to an area where he could shoot more people.

He told police that he wanted to die exchanging fire with law enforcement.

Nehemiah told police that he had taken both of the guns from his parents? closet, and that he had taken a photo of his dead mother and sent it to his girlfriend.

Whether Nehemiah's statement to police can be presented at trial is unclear. Although police say that he was read his Miranda rights, state law demands that prosecutors must prove that the confession was offered only after a "knowing, intelligent and voluntary waiver of the child's constitutional rights was obtained."

The court takes into account the time of day and treatment of the child at the time of questioning, the child's mental and physical condition and whether the child had an attorney, friends or relatives present.

Police and neighbors in Albuquerque were still trying to make sense of what had happened on Monday.

?I?ve never seen anything quite like this,? Bernalillo County Sheriff Dan Houston said at a news conference on Sunday, the Albuquerque Journal reported.

Greg and Sarah Griego were remembered by friends and neighbors as a caring pastor and housewife.

?Chaplain Griego was a dedicated professional that passionately served his fellow man and the firefighters of this community,? said a statement released by the Albuquerque Fire Department. ?His calming spirit and gentle nature will be greatly missed. Our thoughts and prayers go out to Greg?s extended family.?

Neighbor Peter Gomez told the Albuquerque Journal that he did not know Nehemiah Griego well but that the accused teen ?wore nothing but camouflage stuff.?

Few other details about the alleged shooter were clear two days after the killing of his family members. On Monday, a spokesman for the Children, Youth, and Families Department in New Mexico said that Griego has ?no history with the juvenile justice system,? according to the AP.

?Our family is grieving this terrible tragedy,? relatives of the Griego family said in a statement. ?We appreciate the prayers and support we have received and request that the media honor our family?s privacy during this difficult time.?

Griego is expected to make his first appearance in court on Tuesday, according to the AP.

NBC staff writer Isolde Raftery contributed to this report.

Source: http://usnews.nbcnews.com/_news/2013/01/21/16628682-new-mexico-teen-accused-of-killing-family-wanted-to-kill-more-police-say

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Writing Love Notes ? Join the challenge! ? Felix Doolittle Sketches

Petite Love Notes - "Love Spell"

Did you know that ?words of affirmation? are considered a language of love? It can! ?According to New York Times best selling author, Dr. Gary Chapman in the 5 Love Languages,?writing or speaking your gratitude,?appreciation, and love can do wonders to make a loved one feel fabulous about a relationship. Dr. Chapman?s basic idea is that we all have one or two main languages in how we understand and experience love. The five languages are: Words of Affirmation, Acts of Service, Receiving Gifts, Quality Time, and Physical Touch.

That?s where we come in with this year?s Valentine?s gift ?in the language, Words of Affirmation. Petite Love Notes are little love themed note cards for penning sweet nothings (or an apology perhaps) to a loved one. ?Felix created?5 unique collections. ?Here are a few of the sets below. To see the entire collection, click here.

Love Found - Petite Love Notes

Simple Touch - Petite Love Notes

Sweetie - Petite Love Notes

We?re having a Love Note Writing Challenge starting on Valentine?s Day for one month. You decide to write anywhere between 1 and 7 notes a week to your honey(s). ?All loved ones are included. Sign up and we?ll do this love experiment together!? I?ll be writing to both Felix and my son. ?Then,on March 14th, we?ll check back to see if there?s any noticeable positive changes from the practice. ?I hope you?ll join me in this love experiment. Let me know in the comments below! And of course we have the perfect little cards for your sweet nothings? ;D

Love Spell - Petite Love Notes?

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Source: http://fdsketches.com/2013/01/22/speaking-the-languages-of-love/

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Blood-based biomarkers may lead to earlier diagnosis of Parkinson's disease

Jan. 20, 2013 ? Parkinson's disease (PD) is a progressive neurological condition. At present, it is usually diagnosed only when motor features are present. Hence, there is a need to develop objective and measurable biomarkers to improve PD diagnostics during its earlier stage, prior to its motor onset. In this pilot study, researchers identified and tested the first blood-based circulating microRNA (miRNA) biomarkers for PD.

Their results are published in the latest issue of Journal of Parkinson's Disease.

PD is the second most common neurodegenerative disorder in the United States, affecting approximately one million Americans and five million people worldwide. Its prevalence is projected to double by 2030. The most obvious symptoms are movement-related, such as involuntary shaking and muscle stiffness; later, cognitive and behavioral problems may develop along with additional peripheral symptoms such as gastrointestinal dysfunction. There is currently no cure, although the drug levodopa can relieve the symptoms. The differential diagnosis of PD is based primarily on subjective clinical rating scales associated with motor functions. As these scales can only be used when motor features are present, 60-70% of a patient's dopaminergic neurons are already lost by the time of diagnosis.

"The ideal biomarker should be minimally-invasive, cost efficient, quantifiable, reproducible, specific, and sensitive," explains lead investigator Sok Kean Khoo, PhD, of the Center for Neurodegenerative Science and Genomic Microarray Core Facility at the Van Andel Institute, Grand Rapids, Michigan. "Biofluids such as plasma could provide an ideal resource for development of such desirable biomarkers. However, clinical diagnostic tests based on biochemical analysis of biofluids from PD patients have yet to be established," she continues.

Investigators hypothesized that specific miRNAs related to PD can be detected in plasma. It is known that miRNAs detected in various cells and tissues can also be found in biofluids such as blood plasma and serum. A preliminary study using miRNA microarrays showed that approximately 4% (35/866) of miRNAs from healthy brain tissues could also be detected in the plasma of healthy controls.

In an initial study they obtained the global miRNA expressions in plasma of an initial discovery set of 32 PD patients and 32 normal controls and identified nine pairs of PD-predictive classifiers and 13 most-differentially expressed miRNAs as potential biomarkers to discriminate PD patients from normal controls. They then used a quantitative real-time Polymerase Chain Reaction technique (qRT-PCR) to validate and evaluate the performance of these biomarkers in a new replication set of 42 PD patients and 30 controls from the same clinical site.

They then identified a combination of biomarkers that achieved the highest predictive performance and applied this panel of biomarkers to a new, independent validation set of samples from 30 PD patients from a different clinical site, which showed lower biomarker performance.

The investigators acknowledge that there are still challenges to be overcome in validating biomarker candidates due to clinical and sample variability and factors that influence miRNA expression such as comorbidities and other medication the patient is taking. However, explains Dr Khoo, "This is a proof-of-concept study to demonstrate the feasibility of using plasma-based circulating miRNAs, and the hypothesis that miRNA expression changes are associated with the neurodegenerative disease process, either directly or as part of positive feedback loops, is emerging rapidly. This study opens new opportunities to the exploration of circulating miRNAs for diagnostic, prognostic, and therapeutic interventions for PD and possibly other neurodegenerative diseases."

"A diagnostic test to determine the status of a patient's disease onset would provide crucial data for more timely, efficient, and successful therapeutic interventions," said Patrik Brundin, MD, PhD, Director of Van Andel Institute's Center for Neurodegenerative Science. "There is an urgent need to develop objective, measureable biomarkers to improve PD diagnostics and help define its subtypes, and Dr. Khoo's interesting study is an important step in that direction."

Research was supported by the Van Andel Research Foundation, Van Andel Institute's Purple Community: 100% Hope, the Swedish Medical Research Council, the Erling-Persson Family Foundation, the Swedish Parkinson Foundation, the Swedish Parkinson's Disease Association, and The Michael J. Fox Foundation for Parkinson's Research Rapid Response Innovation Award.

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Journal Reference:

  1. Sok Kean Khoo, David Petillo, Un Jung Kang, James H. Resau, Brian Berryhill , Jan Linder, Lars Forsgren, Leslie A. Neuman, Aik Choon Tan. Plasma-Based Circulating MicroRNA Biomarkers for Parkinson's Disease. Journal of Parkinson's Disease, Volume 2/Issue 4 (December 2012) DOI: 10.3233/JPD-012144

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/XjCyG2V6-Sw/130120145842.htm

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Monday, January 21, 2013

Clark Gable's 1955 Mercedes-Benz 300SL Gullwing doesn't sell ...

Clark Gable's 1955 Mercedes-Benz 300SL Gullwing

How much extra value does previous celebrity ownership add to of a car? Really, there's no way to know until the car in question hits the auction block and bidders start raising their hands. In the case of the 1955 Mercedes-Benz 300SL Gullwing you see above, the celebrity owner is none other than Clark Gable, who purchased it new. After Gable's death in 1960, the car changed hands a few times before settling with Charles Wood in 1975.

A high-dollar restoration was performed in 1989, and period accessories added by Gable himself were kept in place, including the Rudge knock-off wheels and Nardi steering wheel. Any Mercedes-Benz 300SL is worth a big chunk of money. In the case of Clark Gable's old Gullwing, the bidding stalled at $1.9 million here at the 2013 Barrett-Jackson auction in Scottsdale. As one of the 5000-series cars, this 300SL carried a reserve, and a bit of after-the-fact dealmaking saw the car change hands for $1.85 million.

You can see our high-res image gallery above, and the car's official auction description below.

*UPDATE: Video added below.


Show full PR text

Barrett-Jackson Lot: 5001 - 1955 MERCEDES-BENZ 300SL GULLWING COUPE

Purchased new by Clark Gable at Mercedes-Benz of Hollywood, Calif. List price was $7,295 FOB NYC. After Gable's death in November 1960, ownership was passed to Harry Haeigen, cartoonist and Gable's publicist. Title passed to Charles Wood, owner of Grand Stand Amusement Park in 1975. In 1989, Mr. Wood commissioned Paul M. Russell of Gullwing Service Company, Inc. of Essex, Mass. To restore this classic at a cumulative cost of nearly $200,000. Gable ditched the standard steel wheels for the racing Rudge knock-offs the car wears now. The wood and chrome Nardi steering wheel replaces the standard white wheel, early photos show the Nardi wheel in Gable's lifetime. The car was featured in the May/June 2006 edition of Motor Trend Classic magazine. At the time the car was subjected to extensive testing that shows it can handle and perform much as it did in 1955. Copies of the 1960s auto registration cards show Clark Gable's signature along with Kathleen "Kay" Sprecker's (5th Wife). Gable signed service orders from Mercedes-Benz of Hollywood for a lube/oil change for $4.00 and parts for $10.83 total. From the Bob Howard Collection.

Source: http://www.autoblog.com/2013/01/19/clark-gables-1955-mercedes-benz-300sl-gullwing-doesnt-sell-th/

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